Interferons are potent stimulators of the body's natural defenses. Not only do cancers have ways to evade these defenses, but some people have a poor ability to mount a defense response to cancers. These natural defenses are often referred to as an "Immune" response. Use of novel activators of the immune response can help fight cancer. Basic science research on liver cancer treatment carried out by investigators of Comprehensive Liver Care of New Jersey focus on how to boost the immune response to fight liver cancer.